October 7, 2024 – Customers frequently ask what swabs are compatible with our iSWAB® non-invasive sample collection technology. Although most swab types can be used with our system, including cotton, dacron, and rayon, we have found that flocked swabs provide the best overall result in terms of DNA yield and quality. But which flocked swab?
To answer this question, we partnered with Tempus AI and Tally Health™ to compare flocked swabs from both Puritan® and Copan, two of the market-leading swab manufacturers. Buccal samples were collected using Puritan® PurFlock Ultra® and Copan FLOQ swabs, stabilized by iSWAB®-DNA, preprocessed and ran on Infinium MethylationEPIC by Tempus AI, and raw data was analyzed by Tally Health™ for epigenetic age prediction. To summarize, there was no significant difference in quality between samples collected by either Puritan® or Copan flocked swabs.
The full study can be seen here: https://www.mawidna.com/article/the-effect-of-swab-type-on-infinium-methylation-epic-data-for-age-prediction/
About Tempus AI
Tempus AI started with the focus of building the first version of a platform capable of ingesting real-time healthcare data in an effort to personalize diagnostics and has built the platform for oncology, having expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Tempus AI builds innovative tech solutions oriented around clinical care and research products—and the virtuous cycle between them.
About Tally Health™
Tally Health™ has created a next-generation test optimized for use in human cheek swabs. This modern test was built using an in-house dataset that includes over 8,000 people, spans a wide chronological age range of 18-100 years, and represents diverse demographic groups. This unique set of data represents the largest DNA methylation adult cheek swab dataset ever generated. With this data, they constructed TallyAge™ using a novel computational approach that maximizes reproducibility and incorporates lifestyle and health factors.
About Mawi DNA
Mawi DNA is a leader in the field of high-integrity sample collection and storage. The company’s innovative tools and advanced protocols ensure the preservation of biological data throughout the collection and storage process, leading to accurate and reliable results. Mawi DNA is committed to providing researchers and scientists with the tools they need to make groundbreaking discoveries in a variety of fields, including agriculture, environmental science, and human health.
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