Article Abstract Within the over 70 reported transforming growth factor-beta–induced (TGFBI) corneal dystrophy mutations,1more than 40 are associated with lattice corneal dystrophy (LCD), subtypes I, III, IIIA, and IIIB according to the Human Gene Mutation Database (QIAGEN, Hilden, Germany). This is a follow-up investigation to a study we published in… read more →
Have you ever wondered why isolating quality DNA from Spit/Saliva is inconsistent, especially when it comes to DNA sequencing? Spit/Saliva is a complex biological matrix with a mixture of different DNA sources that vary in percentage from one individual to another White blood cells Buccal cells Lysed cells… read more →
Here are the differences between Non-Invasive vs Invasive Biosampling.
Traditional non-invasive sample collection has two approaches to try and collect and produce high gDNA recovery. While both methods have benefits, they also have their challenges. Saliva/Mouthwash Self collection, but limited to individuals capable of producing sufficient saliva Collection solution contains alcohol Yields sheared, short-fragment DNA not optimal for complex downstream applications Up… read more →
Saliva Collection is not a Universal Sample Collection Tool: 20% – 46% of the Population Suffers from Dry Mouth Not everybody can produce enough saliva: Collecting 1-2 mL of Saliva within 30 minutes (as required by most saliva collection kits) can be very challenging for a significant portion of the… read more →
Michelle Gordon from Boston University presented her work at the recent AAFS 2018 Conference in Seattle, WA: iSWAB-ID AAFS 2018 Presentation In recognition of her hard work, Michelle was nominated… read more →